BEGIN:VCALENDAR PRODID:-//github.com/ical-org/ical.net//NONSGML ical.net 5.1.4//EN VERSION:2.0 BEGIN:VEVENT DESCRIPTION:Concussion is a highly prevalent injury both in Australia and a round the world. However\, we currently lack clinically validated objectiv e tools to determine its severity or offer prognostic insight. While most people recover from concussion within a few weeks or months\, emerging evi dence suggests that up to 50% of individuals experience post-concussive sy mptoms for more than three months after injury\, a condition termed persis tent post-concussion symptoms (PPCS). It is believed that subtle damage to the brain's white matter\, which continues to evolve and worsen in the we eks and months post-injury\, may be responsible for symptom burden and pro longed recovery time. The microscopic nature of this damage means that it cannot be identified on clinical computed tomography (CT) or clinical magn etic resonance imaging (MRI) scans\, and there are currently no alternativ e objective tests available. Melissa's research investigates novel biomark ers of white matter damage in individuals with concussion in both the acut e and chronic phases. Her work utilizes a novel neuroimaging method\, diff usion MRI\, which allows for microscopic investigation of white matter dam age that is undetectable by current methods. In addition to neuroimaging\, she also explores blood-based biomarkers to provide insight into specific pathological processes associated with post-concussive white matter injur y. The integration of these methods offers a more comprehensive understand ing of the brain after a concussion\, enabling clinical management to be g uided toward early interventions and treatments that alleviate symptom bur den and expedite recovery. DTEND:20240514T111500Z DTSTAMP:20260830T085456Z DTSTART:20240514T094500Z LOCATION:Subiaco Petanque Club SEQUENCE:1 SUMMARY:Concussions - Blood and Neuroimaging Biomarkers UID:cc3c3964-0e15-40e9-be3c-09e5cacd3f29 X-ALT-DESC;FMTTYPE=text/html:

Concussion is a highly prevalent injury bot h in Australia and around the world. However\, we currently lack clinicall y validated objective tools to determine its severity or offer prognostic insight. While most people recover from concussion within a few weeks or m onths\, emerging evidence suggests that up to 50% of individuals experienc e post-concussive symptoms for more than three months after injury\, a con dition termed persistent post-concussion symptoms (PPCS). It is believed t hat subtle damage to the brain'\;s white matter\, which continues to ev olve and worsen in the weeks and months post-injury\, may be responsible f or symptom burden and prolonged recovery time. The microscopic nature of t his damage means that it cannot be identified on clinical computed tomogra phy (CT) or clinical magnetic resonance imaging (MRI) scans\, and there ar e currently no alternative objective tests available.

\n\n

Melissa 9\;s research investigates novel biomarkers of white matter damage in indi viduals with concussion in both the acute and chronic phases. Her work uti lizes a novel neuroimaging method\, diffusion MRI\, which allows for micro scopic investigation of white matter damage that is undetectable by curren t methods. In addition to neuroimaging\, she also explores blood-based bio markers to provide insight into specific pathological processes associated with post-concussive white matter injury. The integration of these method s offers a more comprehensive understanding of the brain after a concussio n\, enabling clinical management to be guided toward early interventions a nd treatments that alleviate symptom burden and expedite recovery.

\n END:VEVENT END:VCALENDAR